Vyvanse is one of the most prescribed ADHD medications in the country. And for good reason. It works smoothly, lasts most of the day, and has a lower risk of the "crash" that other stimulants can cause.
But getting a prescription can feel like a maze. You need a proper evaluation. You need a provider who understands ADHD. And you need it to actually fit your schedule.
That's what this guide covers. How Vyvanse works, how it stacks up against other options, and how to get evaluated and start treatment the same day.
What Is Vyvanse and How Does It Work?
Vyvanse is the brand name for lisdexamfetamine. It's a stimulant, but it works differently than most.
Here's why: Vyvanse is a prodrug. That means it's inactive when you swallow it. Your body has to break it down first. Only then does it convert into its active form (dextroamphetamine) in your bloodstream.
This prodrug design gives Vyvanse two big advantages:
Smoother onset. No sudden spike. The medication ramps up gradually, which means fewer jitters and a more even feeling throughout the day.
Longer coverage. Vyvanse lasts up to 14 hours for most people. That covers your entire workday and then some. Compare that to immediate-release Adderall, which typically wears off in 4--6 hours.
Vyvanse comes in capsule form with doses ranging from 10mg to 70mg. Your provider will start you low and adjust based on how you respond.
Vyvanse vs Adderall: What's the Difference?
This is the most common question people ask. Both are amphetamine-based stimulants. Both treat ADHD effectively. But they're not the same.
Duration: Vyvanse covers 10--14 hours. Adderall XR covers 8--12 hours. Adderall IR covers 4--6 hours.
Onset: Vyvanse takes about 1--2 hours to reach full effect because of the prodrug conversion. Adderall kicks in faster--usually within 30--60 minutes.
Abuse potential: The prodrug mechanism makes Vyvanse harder to misuse. You can't speed up the conversion by crushing or snorting it. This is one reason some providers prefer prescribing it.
Side effects: Both can cause decreased appetite, trouble sleeping, and dry mouth. But many patients report Vyvanse feels "gentler" with fewer peaks and valleys.
Not sure which is right for you? Our guide breaks down every ADHD medication option so you can see the full picture.
If you're curious about what getting an Adderall prescription looks like, we have a full breakdown of that too.
Vyvanse vs Mydayis: Extended Coverage Compared
Mydayis is another long-acting option that some people compare to Vyvanse. Both are designed for all-day coverage, but they work differently.
Mydayis uses a triple-bead release system--three separate releases throughout the day. Vyvanse uses the prodrug mechanism for a single, smooth curve.
Mydayis is only approved for adults (17+), while Vyvanse is approved for ages 6 and up. Some patients who don't get enough coverage from Vyvanse do well with Mydayis, and vice versa.
You can read our complete Mydayis guide for a deeper comparison.
How to Get a Vyvanse Prescription Through ADHD One
Vyvanse is a Schedule II controlled substance. That means you need a legitimate evaluation from a licensed provider before anyone can prescribe it. There are no shortcuts here--and there shouldn't be.
Here's how it works with ADHD One:
Step 1: Schedule your evaluation. You can schedule your evaluation for today. No weeks-long waitlists.
Step 2: Meet with a board-certified provider. Your provider will do a comprehensive ADHD assessment. They'll review your symptoms, history, and goals. This isn't a checkbox exercise--it's a real clinical conversation.
Step 3: Get your prescription. If Vyvanse is clinically appropriate for you, your provider can send the prescription to your pharmacy that same day. If another medication is a better fit, they'll explain why and help you find the right option.
Step 4: Ongoing management. ADHD treatment isn't "one and done." You'll have regular check-ins to monitor how the medication is working, adjust dosing, and handle your prescription refills.
Is Vyvanse Right for You?
Vyvanse tends to work well for people who:
• Need all-day coverage (work, school, evening responsibilities)
• Have had "crash" issues with shorter-acting stimulants
• Want a smoother, more gradual onset
• Are concerned about the abuse potential of other stimulants
It may not be the best fit if you:
• Need something that kicks in fast for morning focus
• Are sensitive to stimulants in general (a non-stimulant like Qelbree might be worth exploring)
• Have certain cardiovascular conditions (your provider will screen for this)
The only way to know for sure is a proper evaluation. Every person's brain chemistry is different.
Insurance and Cost
Vyvanse recently went generic (August 2023). That's a big deal. The brand-name version used to cost $300--$400/month without insurance. Generic lisdexamfetamine is significantly cheaper.
Most insurance plans cover Vyvanse or its generic. Your provider can help navigate prior authorization if your plan requires it.
If cost is a concern, bring it up during your evaluation. There are almost always options--different medications, manufacturer coupons, or dosing strategies that can help.
Think You Might Have ADHD?
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Take the Free ADHD TestFrequently Asked Questions
Can you get a Vyvanse prescription online?
Yes. DEA regulations allow licensed providers to prescribe Schedule II medications like Vyvanse after a proper clinical check-up. ADHD One's licensed providers conduct full ADHD assessments and can prescribe Vyvanse when clinically right.
The key requirement is a legitimate check-up--not just a questionnaire. Your provider needs to assess your full symptom history before making any prescribing decision.
Is Vyvanse a controlled substance?
Yes. Vyvanse (lisdexamfetamine) is classified as a Schedule II controlled substance by the DEA. This is the same classification as Adderall and Mydayis. It means prescriptions can't be called in by phone in most states--they must be sent electronically or on a special prescription pad.
The prodrug mechanism does make Vyvanse harder to misuse than some other Schedule II stimulants, which is one reason many providers favor it.
Vyvanse vs Adderall--which is better for ADHD?
Neither is universally "better." They work differently and suit different people. Vyvanse lasts longer (up to 14 hours vs 8--12 for Adderall XR), has a smoother onset, and carries a lower abuse risk due to its prodrug design. Adderall kicks in faster and comes in more flexible dosing options.
The right choice depends on your daily schedule, how you respond to each medication, and your provider's clinical judgment. Many patients try both before settling on one.
How long does Vyvanse take to start working?
Most people notice effects within 1--2 hours after taking Vyvanse. It takes longer than Adderall because your body has to convert the prodrug into its active form. Peak effects usually hit around 3--4 hours after dosing and taper gradually over the rest of the day.
This slower ramp-up is actually a feature, not a bug. It's what gives Vyvanse that smooth, steady feeling instead of a sudden "on switch."
What happens if Vyvanse doesn't work for me?
That's completely normal and more common than you'd think. ADHD medication is not one-size-fits-all. If Vyvanse isn't the right fit, your provider will work with you to try other options--whether that's a different stimulant like Mydayis or Adderall, or a non-stimulant approach.
The goal is finding what works for your specific brain chemistry. That sometimes takes a couple of tries, and that's okay.